Oncotarget: The Research Body That Finds Cancer Solutions

One of the most trusted medical journals today would be Oncotarget. It is right now the database of all the reliable academic research and information that many people in the world rely on. One of the latest articles that are being published by Oncotarget today would be the Fox 06 Transcriptional Factor in Breast Carcinogenesis. To learn more about the information, you may want to read on.

The Journal Results

It is shown in the report being published that the FOXO transcriptional factors today would be the four members of carcinogenesis in mammals. The FOXO family is also reported to be some of the causes of breast cancer. Right now there’s poor research so far on what these elements are. However, with Oncotarget’s research, there may now be more potential in finding out more about what causes the medical carcinogen issues. It is also shown in the report from ResearchGate that the overexpression of the human FOX06 would result in the likelihood of having breast tumors. The existence of such gene expression would also be responsible in the proliferation of the breast cancer cells in the body. Check the journal at SCImago Journal & Country Rank.

Oncotarget’s Latest Discoveries

One of the most exemplary studies that EurekaAlert is able to pursue today is the one about how researchers in the Oncotarget database is researching for novel therapeutic ways to understand and cure thyroid cancer. In the press release by Oncotarget, it was shown that there is an abundance among researchers and cancer specialists about the ways in which the thyroid cancer symptoms will be decreased and abated. With Oncotarget’s reputation of only providing the best service in the industry, this aim of researching for the best therapies will not be hard to achieve.

Learn more: https://www.ncbi.nlm.nih.gov/pmc/journals/1558/

An interesting part about Oncotarget’s research for the therapeutic ways is the discovery of the PTC genetic hallmark, which is mostly a mutation of the commonly discovered BRAF gene. Patients who present the BRAFV600E mutation has been referred to the doctors so that they can get a drug called vemurafenib, which will help them cope with the mutation. With such therapy, it’s now easier to find ways to get the cause of the cancer and remedy it. Download output styles at Endnote.com

Dr. Clay Siegall Continues To Improve Cancer Treatment

One of the most exciting developments in the fight against cancer in the last few years has been the advancement of targeted therapy drugs. The Seattle-based firm Seattle Genetics founded and led by Dr. Clay Siegall has become an industry leader in this exciting and comparatively new field. The mortality rate has not substantially improved for certain diseases in decades, and Dr. Siegall and his associates at Seattle Genetics are working toward changing that.


What started as a small startup with only a few researchers in 1998 has grown into one of the industry leaders in cancer research. Seattle Genetic has developed the first FDA-approved drug of this type and now has multiple approved applications leading to over 20 partnerships with pharmaceutical companies such as Pfizer, Genentech, and several others. Dr. Siegall is very excited about the future of the company, citing the growing list of new drugs in development stages and the increasing number of potential applications for his existing portfolio. Believing traditional forms of cancer treatment are destined for obscurity and will be replaced with targeted drug therapies as they are more tolerable and much more efficient. Dr. Siegall is confident Seattle Genetics will be a leader in the drug development industry for the 21st century.


Clay Siegall has always been interested in medicine, and the influence technology can have in the treatment of disease. He became interested in cancer treatment while studying zoology at the University of Maryland where he earned a B.S., he also holds a Ph.D. in genetics from George Washington University. While attending the University of Maryland, a member of his family was afflicted with cancer. He soon discovered the treatment was almost worse than cancer itself, the chemotherapy almost caused his family member to die. Other forms of treatment such as radical surgery and amputation convinced him there had to be a better way.


Before founding Seattle Genetics where he is the current CEO Dr. Siegall worked at the Bristol-Myers Squibb Pharmaceutical Research Institute. Dr. Siegall left Bristol-Myers for several reasons, he did not like the restraints and felt he was not adequately compensated for the work he was doing. Citing one of his patients, he holds nine, that made Bristol-Myers $80 million and all he saw was a paycheck. Dr. Siegall has authored over 65 scientific articles and serves on the board of three scientific journals.